CEFAZOLIN ACID
Cefazolin
CAS: 25953-19-9
Molecular Formula: C14H14N8O4S3
CEFAZOLIN ACID - Names and Identifiers
| Name | Cefazolin |
| Synonyms | Cefamedin Cefamezin cefamezin Cefazolin CEFAZOLIN CEFAZOLIN ACID Cefazolin,sodium salt Cephazolin,sodium salt azol-1-yl)acetyl]-amino]-5-thia-1-azabicylo 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,3-(((5-methyl-1,3,4-thia 7-(1-(1h-)-tetrazolylacetamido)-3-[2-(5-methyl-1,3,4-thiadiazolyl)thiomethyl]d (6r-trans)-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[[(1h-tetr (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (6R,7R)-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[[1-oxo-2-(1-tetrazolyl)ethyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| CAS | 25953-19-9 |
| EINECS | 247-362-8 |
| InChI | InChI=1/C14H14N8O4S3/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26)/t9-,12-/m1/s1 |
CEFAZOLIN ACID - Physico-chemical Properties
| Molecular Formula | C14H14N8O4S3 |
| Molar Mass | 454.51 |
| Density | 2.01±0.1 g/cm3(Predicted) |
| Melting Point | 198-200 C |
| Solubility | DMSO (Slightly), Methanol (Very Slightly, Heated) |
| Appearance | needle |
| Color | White to Off-White |
| pKa | pKa 2.15 (Uncertain) |
| Storage Condition | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| Stability | Hygroscopic |
| Refractive Index | 1.961 |
| Physical and Chemical Properties | Needle-like crystals. Melting Point 198-200 ° C (decomposition), soluble in DMF, pyridine, soluble in acetone, ethanol, methanol-soluble, insoluble in chloroform, benzene, ether. Its sodium salt ([27164-46-1]) is a white or yellowish powder. Insoluble in methanol, ethanol, insoluble in acetone, chloroform. It is stable when drying, and the stability of the aqueous solution is poor. |
| Use | It is a semi-synthetic broad-spectrum cephalosporin, and its antibacterial mechanism, antibacterial spectrum and adaptability are similar to those of cephalothin |
CEFAZOLIN ACID - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 2941906000 |
CEFAZOLIN ACID - Upstream Downstream Industry
| Raw Materials | 1-Phenyl-1H-tetrazole-5-thiol 2-Mercapto-5-methyl-1,3,4-thiadiazole 1H-Tetrazole-1-acetic acid |
CEFAZOLIN ACID - Reference
| Reference Show more | 1. Zhang Zheng, Ma gengqin, Wang Hongxuan, Hou Wenfu, Zhou Min. Biological characteristics and multi-drug efflux pump expression of drug-resistant Vibrio parahaemolyticus [J]. Modern food science and technology, 2020,36(08):15-22. |
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Raw Materials for CEFAZOLIN ACID